Amcloren

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Vendor: Juptor Technical

Each capsule contains Ampicillin Trihydrate B.P equivalent to Ampicillin 250mg and Cloxacillin Sodium B.P equivalent to Cloxacillin 250mg.

Category: Beta-Lactam Antibiotics

Brand:Abacus Rene Industries

Product Description

INTRODUCTION:
Amcloren is a broad -spectrum formulation of Ampicillin Trihydrate (6 amino- penicillianic acid) and Cloxacillin Sodium (isoxazolyl penicillin) having a broad-spectrum activity against a wide range of Gram-negative and Gram-positive bacteria.
MICROBIOLOGICAL ACTION:
Amcloren is active against a wide range of Gram-negative and Gram-positive bacteria including Streptococci, Staphylococci (penicillinase producing strains), Haemophilusinfluenzae, Escherichia coli, Proteus mirabilis, Salmonella species, and Neisseria species.
MECHANISM OF ACTION:
Both Ampicillin and Cloxacillin are bactericidal agents. They act by interfering with synthesis of the peptidoglycan layer of the cell wall, which normally protects the bacterium from its environment. Defective wall synthesis renders the cell incapable of withstanding the osmotic gradient between the cell and its environment so that it swells and explodes. Synergy has been demonstrated between Ampicillin and Cloxacillin against some beta-lactmase producing organisms.