Ciproren

Name: Ciproren
SKU: 11452
Availability: InStock

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Vendor: Juptor Technical

Each tablet contains Ciprofloxacin Hydrochloride BP. equivalent to Ciprofloxacin 500mg.

Category: Antibiotics (Bacterial Infections)

Brand:Abacus Rene Industries

Product Description

MICROBIOLOGICAL ACTION
Ciprofloxacin is active against a wide range of gram-negative and gram-positive pathogens including strains resistant to penicillin, cephalosporins and/or aminoglucosides.
Ciproloxacin is effective against both replicating strains of bacteria in stationary phase. It is also effective against intracellular bacteria. It has significant post-antibiotic effect and thus prevents the regrowth of bacteria. The broad spectrum activity of Ciprofloxacin includes the following organisms:
Gram-negative bacteria:
Enterobacteriaceae: E. coli, Klebsella species, proteus species, Enterobacter species, Morganellamorganii, Citrobacter species, Serratia species and providenca species.
Pseudomonadacea: Pseudomonas aeruginosa and Pseudomonas cepacia.
Enteropathogenic: Salmonella, shigella species Enteropathogenic E. coli, Y. enterocolitica, A. hydrothilla, V.cholerae, Campylobacter jejuni& Arizona species.
Miscellaneous; N. gonorrhoeae, Pasteurella, Moraxella and GardnerellaVaginalis.
Gram-Positive bacteria.
Staphylococcus aureus including penicillinase-producing and methicillin-resistant strains; staph epidermidis, Strep.Pyogenes, Strep. Agalactiae, Strep. Pneumoniae, Strep. Viridans and Listeria monocytogenes.
Intra-cellular bacteria-resistant strains:
Chlamydia trachomatis, Mycoplasma hominis, Legionella species,
Brucella species; Anaerobes including most species of Bacteroids; Clostridium and Fusobactrium.
MECHANISM OF ACTION
Ciprofloxacin is a fast acting bactericidal agent. It interacts with A and B subunits of DNA gyrase and disrupt the DNA function leading to the death of bacteria. Bacterial, resistance with Ciprofloxacin is low and it even eliminates plasmid mediated resistance.
PHARMACOKINETICS
Ciprofloxacin is rapidly absorbed after oral ingestion. It enters most of the body compartments in which infections occur. The serum half life ranges from 3.0-3.4 hours after oral administration and the volume of distribution is more than 100 liters.
INDICATIONS
Respiratory tract infection: Acute bronchitis, infected bronchiectasis, and lung abscess exacerbation of chronic obstructive airways disease, empyema, cystic fibrosis and pneumonia.
Urinary tract infection: Acute and chronic pyelonephritis, prostatitis, cystitis, epididymitis and chronic complicated or recurrent UTI caused by multi-resistant organisms and / or Pseudomonas aeruginosa.
Skin and soft tissue infections: In surgical and postoperative wounds infections due to gram-negative organisms such as Enterobacteriaceae and pseudomonas aeruginosa. Also useful in infections caused by resistant staphylococci e.g. infected ulcer, cellulites, otitis extema, infected burns etc.